Preclinical R&D Strategy

Simultaneous target–indication screening: A game of 3D chess

Simultaneous target–indication screening: A game of 3D chess

Simultaneous target–indication screening:
A game of 3D chess

Selecting the right target and lead indication is one of the most critical choices in a biotech’s trajectory, yet it is rarely straightforward.

For platform organizations, the challenge grows as the search spans millions of potential combinations, far beyond what traditional reviews or internal capacity can manage effectively.

In this white paper, Scitaris co-founder Jonathan Vonnemann, PhD and senior consultant Wignand Mühlhäuser, PhD discuss how structured search and prioritization frameworks help preclinical teams:

  • Align with biological, regulatory, commercial, and clinical realities  
  • Quickly gain clarity on complex target-indication choices
  • Reduce development and investment risk
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FAQ

Do I have to have a PhD in the life sciences to work at Scitaris?

Yes. We also assess cognitive ability; successful candidates typically score within the top 5%. Occasionally, we hire for non-consulting roles where experience and relevant expertise may be more important than a PhD.

Do you leverage experience from treating physicians in your analyses?

Yes. We interview key opinion leaders (e.g., healthcare providers and other subject matter experts) to complement analyses as needed.

Do you support different global or regional regulatory strategies?

Yes. We integrate regulatory perspectives into our development strategies and can adapt approaches for FDA, EMA, PMDA, and other regional authorities. This ensures clinical plans are aligned with regulatory expectations worldwide.

Can we include side entries in the analysis?

Yes. Side entries and inbound lists from investment banks can be integrated at any stage.

Have a specific question?
Contact us and see how we can help.

Ready to help build the future of biopharma strategy?